Certified Tissue Bank Specialist (CTBS) Practice Test

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What is the allowable residual level of ethylene chlorohydrin in ppm for processed MS tissue?

  1. 25

  2. 100

  3. 250

  4. 2500

The correct answer is: 250

The allowable residual level of ethylene chlorohydrin in processed musculoskeletal tissue is set at 250 ppm. This level is established based on safety assessments and regulatory guidelines that aim to minimize potential risks associated with residual chemicals in tissue for transplantation. Ethylene chlorohydrin is a chemical used in the sterilization process, and its presence must be strictly monitored to ensure that tissue products are safe for patients. Regulatory bodies have determined that keeping this residual level at or below 250 ppm is necessary to safeguard against any adverse effects that could result from higher concentrations of this compound. Setting the maximum allowable limit at 250 ppm balances the need for effective sterilization with the safety concerns regarding potentially harmful residues. This regulation is critical for maintaining the integrity and safety of transplantable tissues, assuring healthcare providers and patients that the tissues have been properly processed without hazardous levels of remaining chemicals.